COVID-19, adrenal gland, glucocorticoids, and adrenal insufficiency
نویسندگان
چکیده
The current Coronavirus disease outbreak requires that physicians work in collaboration with other especially intensive care and emergency units. To fight against this new disease, whose pathogenesis, effects, results have not been clearly demonstrated, patients the pre-existing chronic special expertise perspectives. Due to need for dynamic glucocorticoid treatment at different stages of adrenal insufficiency, existence reports indicating "coronavirus 2019" also affects reserve, use glucocorticoids advanced require issue be emphasized precision. Herein, insufficiency actual effects critical on gland reviewed.
منابع مشابه
Adrenal insufficiency.
Adrenal insufficiency is the clinical manifestation of deficient production or action of glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens. It is a life-threatening disorder that can result from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic-pituitary axis. Prompt diagnosis and management are essential. The c...
متن کاملAdrenal insufficiency.
Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis. In children, the most common causes of primary adrenal insufficiency are impaired adrenal ster...
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The activity of phenylethanolamine-N-methyl transferase, an enzyme that synthesizes adrenaline from noradrenaline in the adrenal medulla, is markedly depressed following hypophysectomy. Enzyme activity is restored to normal after administration of ACTH or the potent glucocorticoid, dexamethasone. Thus the biosynthesis of adrenaline in the adrenal medulla appears to be regulated by the pituitary...
متن کاملAdrenal insufficiency.
Adrenal insufficiency is caused by either primary adrenal failure (mostly due to autoimmune adrenalitis) or by hypothalamic-pituitary impairment of the corticotropic axis (predominantly due to pituitary disease). It is a rare disease, but is life threatening when overlooked. Main presenting symptoms such as fatigue, anorexia, and weight loss are non-specific, thus diagnosis is often delayed. Th...
متن کاملAdrenal insufficiency.
A 44-year-old woman reported several weeks of fatigue, somnolence, pain in the large joints, nausea, and decreased appetite. She had also noted an unintentional 11-kg weight loss over a period of 6 months. She had a remote history of amenorrhea, but she was presently menstruating regularly. She was taking no medications, with the exception of acetaminophen as needed for knee pain. The diagnosis...
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ژورنال
عنوان ژورنال: Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic
سال: 2021
ISSN: ['1213-8118', '1804-7521']
DOI: https://doi.org/10.5507/bp.2021.011